The Science Behind the Technology
A scientific, evidence-based approach for the clinical utilization of ERPs
The Science Behind the Technology
A scientific, evidence-based approach for the clinical utilization of ERPs
Progression from EEGs to the NeuroCatch™ Platform
EEG
- Objective
- Neuro-physiological cognitive assessment
ABC
- A = Auditory Sensation (N100)
- B = Basic Attention (P300)
- C = Cognitive Processing (N400)
NeuroCatch™ Platform
- Software + hardware
- Elicits, acquires, analyzes, stores, reports, and manages ERP info for ABC
- Accessible to clinics
The NeuroCatch™ Platform provides:
A scientific, evidence-based approach for the clinical utilization of ERPs
An objective, neuro-physiological assessment using ABC (Auditory Sensation [N100]; Basic Attention [P300]; and Cognitive Processing [N400])
Evolution of the Brain Vital Signs™ Framework
Spearheaded by leading Simon Fraser University neuroscientist Dr. Ryan D’Arcy, HealthTech Connex is working to deliver Brain Vital Signs™, a new framework for analyzing complex brainwave data that will provide simple, practical and objective physiological markers of brain function. Learn more about Brain Vital Signs™.
Completed and Ongoing Clinical Studies
Using the NeuroCatch™ Platform
| Study Title | Status | Conditions | Location | Reg. No. |
|---|---|---|---|---|
| Assessing Repeatability of NeuroCatch™ Platform Measurements: An Initial Assessment | Completed |
|
HealthTechConnex Inc. Centre for Neurology Studies Surrey, British Columbia, Canada |
ClinicalTrials.gov: NCT03421405 |
| Preparing to Treat Concussions in Hockey Players Using a “From Ice to Axon and Astrocyte Repeated Measures Design” | Recruiting Complete |
|
Mayo Clinic Rochester, Minnesota, USA |
Site IRB: 18-004925 |
| Development of a Reference Interval Database With the NeuroCatch™ Platform | Recruiting |
|
HealthTechConnex Inc. Centre for Neurology Studies Surrey, British Columbia, Canada |
ClinicalTrials.gov: NCT03835962 |
| Neurophysiological Measurements Using the NeuroCatch™ Platform in Pediatric Concussion | Recruiting |
|
Alberta Children’s Hospital, Department of Paediatrics Calgary, Alberta, Canada |
ClinicalTrials.gov: NCT03889483 |
| Assessing Brain Changes Throughout the WCBH Program | Recruiting |
|
HealthTechConnex Inc. Centre for Neurology Studies Surrey, British Columbia, Canada |
ClinicalTrials.gov: NCT03889483 |
| Longitudinal Validation of a Computerized Cognitive Battery (Cognigram) in the Diagnosis of Mild Cognitive Impairment and Alzheimer’s Disease | Recruiting |
|
BruyereResearch Institute Ottawa, Ontario, Canada |
ClinicalTrials.gov: NCT03676881 |
Peer Reviewed Background Papers
N100
The N1 Response and Its applications
Hyde 1999
P300
Clinical application of the P300 event-related brain potential
Updating P300: An Integrative Theory of P3a and P3b
N400
Thirty years and counting: Finding meaning in the N400 component of the event related brain potential
Electrophysiological assessment of language function following stroke
Brain Vital Signs
Learn More
Learn more about the platform and the next steps if you are interested in incorporating this technology into your research studies.
[1] Luck, S. J. An Introduction to the Event-Related Potential Technique. (MIT Press, 2014)
[2] Duncan, C. C. et al. Event-related potentials in clinical research: Guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400. Neurophysiol Clin 120, 1883–1908 (2009)